Gut Microbiome Product Reviews

Mouth Health

The first line of defense for the entire immune system. Where your oral microbiome goes, your health goes.

On one hand, the gut microbiome enjoys recognition as the primary hub of the body’s microbiome.

After all, each of the body’s different microbiomes — the mouth, nose, ears, throat, stomach, skin, and vagina — are all directly influenced by the microbes that live in the gut.

However, as important as the gut microbiome is, it’s deeply influenced by another microbiome: the oral microbiome.

Gateway to the Gut

The mouth is the primary entry point for all microbes that enter the body.

Seeing that the mouth is moist, exposed to the air, and rich with nutrients, it should be no surprise that the mouth’s microbiome is rich and diverse — brimming with microbial life at all times.

The oral cavity has the second largest and diverse microbiota after the gut, harboring over 700 species of bacteria.

It’s not just bacteria, too. Viruses and fungi are also present in the mouth and, quite often, strong pathogens such as protozoa.

Each day, trillions of microbes are swallowed — directly influencing the microbial populations in the gut.

This daily exposure to endless microbes can overwhelm a weak immune system and populate the gut with hostile microbes.

The Entire Body Is Affected

Left unchecked, microbes in the mouth can chronically activate the immune response — leading to system-wide inflammation in the body and even many systemic diseases:

  • Rheumatoid Arthritis
  • Type 2 Diabetes
  • Adverse pregnancy outcomes
  • Cardiovascular disease
  • Digestive diseases
  • Alzheimer’s disease

The cause of Alzheimer’s might be microbes living in the mouth.

These oral microbes create acids to ward off other species of microbe. However, the mouth’s immune response to oral microbes is to create acids that are much more damaging to the teeth (and fillings) than the pathogens’ own acids. Therefore, a mouth full of unchecked microbes will lead to disastrous tooth decay.

The ongoing presence of stubborn pathogens in the mouth creates a toxic sequence of events that inflames the body, rots the teeth, and, ultimately, leads to systemic disease. Microbes enter the bloodstream via the gums and then travel all around the body, activating the immune system and causing inflammation.

A pernicious cycle develops over time as infection, inflammation, dental decay all cause each other, creating compounding symptoms and disease states.

A Potential Weak Link

The teeth, themselves, can be fragile in youth as well as in aging.

But, it’s often overlooked that teeth are especially vulnerable in chronic illness.

Dental plaque and the surface of the tongue are among the densest microbial habitats on Earth. Bacteria are pretty much wall to wall in there.

Decaying, damaged, or poorly repaired teeth represent an opportunity for microbes to hide, reside, and thrive indefinitely.

When the body is weak, teeth can become both shelter and food for pathogens. Decaying, weak teeth are a source of nutrients for microbes.

The Path Forward

To give the body its best chance for health, recovery, and longevity, it’s important for the following steps to occur:

  • Teeth must stay clean
  • Pathogens must have nowhere to hide
  • Chronic immune system activation must be reduced

When oral health has suffered, it’s important to protect and improve the mouth’s microbiome throughout the day, every day.

Your Oral & Dental Routine


Rinse After Any Food

It’s not common to clean one’s teeth after every meal.

However, in chronic illness and aging, it’s critical to do just that.

Of course, it isn’t always convenient to brush your teeth after each meal and snack. But it can be very easy to rinse and swish for 60 seconds (or longer) — almost anywhere you go.

A small, travel-size bottle of tooth powder can be a gamechanger, leaving you always ready to clean your mouth after you eat.

Tooth Powder

Rather than leaving the mouth coated with food particles — which feed and grow microbes — a good tooth powder refreshes, sanitizes, and even repopulates, depressing microbial activity in the mouth and, in the case of this product, replenishing with a strain of beneficial bacteria.

If we can’t fully remove all food particles from the mouth — which is only possible via brushing and flossing — we must keep the microbial activity in the mouth suppressed until we can fully clean the teeth, tongue, gums, and other oral surfaces.

Uncle Harry’s Tooth Powder

View Christopher’s Herbal Tooth & Gum Powder on iHerb.

TheraNeem Tooth Powder

Also available on iHerb.

A quality tooth powder is, essentially, an all-natural toothpaste with solid ingredients including antimicrobial herbal extracts, Vitamin D, minerals, and even oral probiotics.

It’s good to keep a bottle in the car, at work, and perhaps in a few places around the house (such as the kitchen), where having the ability to quickly clean the mouth might prove useful.

Rinse After Snacks, Too

Keep a tooth powder bottle handy — in your purse, car, or desk at work — so you can rinse and swish after snacks, too.

A snack can introduce just as much organic matter into the oral cavity as a full meal.

Rinsing and swishing isn’t as effective as fully brushing and flossing — but it can protect the enamel from microbial fermentation of your food, and limit the need for an immune response in your gums (which is incredibly damaging to teeth).

Cleaning Throughout the Day

With a bottle of tooth powder nearby, we can easily swish and rinse following all meals and snacks, anytime.

You can also create your own mouth rinse using charcoal, ozone, essential oils, and other compounds — as we’ll discuss further.

Swish for 1-5 minutes after each meal or snack.


A Full Routine

Brush + Floss + Swish

Before bed, combine multiple steps to thoroughly remove all lodged food, plaque, and microbial biofilms from the mouth.

Three Steps For An Effective Evening Routine

  • Floss
  • Brush
  • Swish

An evening routine can be additionally be used in the morning, though it shouldn’t be a replacement for the evening.



It’s easy to forget about flossing — but it’s the only way to remove trapped food particles and plaque in between the teeth.

Floss before brushing the teeth. Be gentle on the gums while flossing — don’t overdo it by causing damage to already-inflammed tissues.

Floss Picks

Also available on iHerb.




Brushing further scrubs away microbial biofilms, plaque, and food particles.

It’s important to scrub the tongue, gums, roof of the mouth and inside of the cheeks with the toothbrush.

Then brush with tooth powder or your favorite toothpaste.

Uncle Harry’s Tooth Powder

View Christopher’s Herbal Tooth & Gum Powder on iHerb.

TheraNeem Tooth Powder

Also available on iHerb.

You can both rinse and brush with these amazing, amazing tooth powders.


Gum Oil or Mouthwash

(Optional, but a good idea)

Essential oils and mouthwash discourage microbial activity throughout the mouth.

In fact, they are shown to be as antimicrobial as fluoride when topically applied. Essential oils are a main reason Listerine is so antimicrobial (although the drying-effect of alcohol in Listerine makes it a subpar choice, long-term).

This antimicrobial effect seems to last for some time in the mouth, giving the immune system a breather and making life hostile for opportunistic pathogens. Essential oils even penetrate the gums and gumline, helping sanitize deep into the tissues of the mouth.

There is considerable evidence that essential oils have potential to be developed as preventive or therapeutic agents for various oral diseases.

After brushing the teeth:

  • Apply 1-2 drops of oil to toothbrush, or apply to the gums with finger.
  • Brush and/or swish for a moment, then spit out.
  • Do not aggressively rinse, let a hint of the essential oils to keep refreshing the mouth.

Theraneem Tooth & Gum Oil

Also available on iHerb.

Some essential oils (clove, neem) are renowned for improving dental health, as well as for having some therapeutic value in a dental crisis.

Many mouthwash products include questionable ingredients, such as carrageenan or glycerin, which are purported to counteract other positive effects of the product.



Exceptional for swishing. But for Brushing?

Charcoal is becoming an extremely popular ingredient for oral health. It’s quite effective for polishing and removing stains on the teeth.

This is, in part, because charcoal has a strong negative charge, enabling it to remove plaque (which is positively-charged) from the negatively-charged teeth.

Charcoal is also antimicrobial and adsorptive, meaning it readily soaks up anything it comes into contact with in the mouth: endotoxins, tartar, and pathogens.

However, there is little evidence demonstrating that charcoal is safe for regular brushing — and some health professionals worry that prolonged brushing with charcoal might erode enamel.

Therefore it’s most likely best to use charcoal only as a mouthwash — swishing after meals or at night during the evening routine.

The good news, charcoal is incredibly effective when being used exclusively as a rinse — without brushing.

Anthony’s Activated Charcoal

View Country Life Activated Coconut Charcoal Powder on iHerb.

Enhancing With Charcoal

Upgrade your nightly routine by creating your own charcoal powder. Consider adding other powdered ingredients.

Powders to include in a charcoal rinse:

  • Neem powder — antimicrobial, antioxidant
  • Sea salt — antimicrobial, reduces acidity
  • Xylitol — antimicrobial (also sweetens)
  • Erythritol — antimicrobial (even more effective than xylitol)

Pre-Made Charcoal Products





On one hand, it’s certainly possible that fluoride is likely harmful to internal bodily tissues, potentially leading to calcification of joints and flesh among other problems — including promoting the accumulation of heavy metals in humans and disruption of bird habitats around lakes.

On the other hand, fluoride is also incredibly antimicrobial against microbes in the mouth. Fluoride disrupts pathogens’ enzyme receptors and weakens microbes’ resistance to acids.

Is there a difference between drinkingingesting via tap water — fluoride into the body (with its effects on the gut microbiome, joints and tissues)…

…and applying it topically in the mouth?

After nearly a decade of personally avoiding fluoride in both drinking water and oral products, I now consider that it might be a good idea to use a fluoride rinse 1-2x/week, simply to boost hostility of the mouth toward pathogens. It can also strengthen enamel in the right doses (daily or weekly topical applications, not drinking).

Fluoride may not be a make-or-break ingredient for your mouth health. But it’s nice to have a safer way to take advantage of its benefits (topical swishing rather than drinking it in tap water) without incurring too much risk.

ACT Total Care Fluoride Mouthwash

A glass of city water usually has about the same amount of fluoride as a small serving of fluoride toothpaste.

Fluoride may not be necessary for optimal oral health — if you’re willing to put in extra work. Remember, many essential oils are just as antimicrobial as fluoride.

If you do wish to use fluoride topically (rather than ingesting it), it can most likely be done safely, even if only used as a rinse several nights per week.

If Desired, swish 1-2x/week for 30 seconds to increase hostility against microbes in the mouth.


Ozone is rapidly becoming a component of holistic dentistry.

Dental ozone use has a good amount of preliminary research into its clinical efficacy. Consider this passage from a 2019 study:

At the dentist’s office, several methods exist for applying ozone to the teeth and gums, but the most typical is insufflation where ozone gas is applied to the dental arch.

Ozone is also sometimes injected into cavitations — abscesses which can result from infected tooth extractions.

Ozonated Water

Ozonated water can be made in minutes with a specialized ozone generator.

Freshly prepared ozonated water showed a statistically significant reduction in [Mutans Streptococci] counts after an interval of 7 days and 14 days when compared to Chlorhexidine.

The standard for killing most microbes is 0.3 ppm ozone with 3 minutes of exposure — although this standard varies based on the smoothness of a surface.

Swishing with ozonated water makes an excellent additional step in any evening routine.

A2Z Ozone Aqua-6 Multi-Purpose Ozone Generator

Ozonate water for 3-5 minutes in a glass. Then, swish in the mouth for 2-3 minutes.

Oil Pulling

Oil pulling produces excellent results for some people but consistency and time is required.

Several studies demonstrate that oil pulling does, in fact, have some antimicrobial properties.

When oil mixes with saliva it emulsifies and produces some compounds with saponification properties — also known as soap.

Therefore, there’s no reason not to oil pull as often as is convenient, even if the toxin-removal effects are only limited (we really don’t know one way or the other).

Be sure to spit into a trash can instead of the sink.

Oil pulling can be augmented by including a drop of gum oil in the mixture.

Pur03 Ozonated Oil w/Peppermint

This ozonated oil is fantastic for the mouth — it leaves the mouth feeling clean and fresh, even through the night.

The effects are most likely due to the presence of the essential oil and the ozone as much as the oil.

Swish olive oil or coconut oil for 5-10 minutes. Add essential oils (1-2 drops) to the mixture as desired.


It’s important to replace your toothbrush (or electric brush head) very frequently — every 2-3 months, minimum.

It doesn’t make sense to reduce pathogenic presence in the mouth, only to reintroduce it with each brushing.

Cleaning A Toothbrush

To reduce microbial life on your toothbrush, soak it once per week for about 10-20 minutes in one of the following solutions:

A toothbrush should still be replaced on time, even with regular weekly sterilization.

Clean toothbrush weekly. Replace Every few months.


The health of the mouth is a key component of gut health as well as the function of the entire body.

Oral and dental health commonly suffers in chronic illness and aging.

In both scenarios, it is imperative to support the body’s immune system by continually improving the microbial health of the mouth — to keep it clean.

RECAP: The steps for sustainably improving oral health

  • Tooth powder swishing after each meal or snack is a potent first step toward better oral health.
  • A solid, multi-step evening routine that includes 1) flossing, 2) brushing, and 3) swishing is essential. This routine is also useful in the morning.
  • Creating your own charcoal swish (possibly with neem powder) can be a fantastic step to augment your regimen.
  • Using ozone or fluoride several times per week (or both) could improve the oral microbiome drastically — especially in the more compromised mouth typically seen in severe immunosuppression or aging.

Nutrients For Oral Health

3 Rules of Nutrient Supplementation

The fat-soluble vitamins are vital to the health of the teeth and gums, as is Vitamin C.

Minerals are also foundational to the health of the teeth, and as with all nutrients, they must be in balance with each other as well.

It’s important to understand how to obtain these nutrients in a balanced and thoughtful way. Overnutrition and imbalance can be just as detrimental as nutrient deficiency.

Read more.

Dental Professionals

Of course, dental professionals and regular checkups are entirely necessary to fix any broken teeth, dental fillings or prosthetics.

Root canals essentially leave dead material inside the mouth, and as such is very prone to rotting. Decay indicates the presence of pathogens — always — and this means infection and illness.

Because microbes and pathogens so easily work their way inside existing dental work it is paramount to diligently keep the mouth exceptionally clean.

Ask pertinent questions of your dental providers. Respectfully get a feel for their competence. Improperly installed dental work can lead to infectious issues down the road — and all the chronic diseases that come with infection.

Uncle Harry’s Natural Remineralization Kit

If you’re looking for a starter pack — this is an excellent brand to check out. Several of my clients have reported excellent results.

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